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a bibo:Issue;
dcterms:medium ;
rdau:P60049 ;
rdau:P60050 ;
rdau:P60048 ;
dc:identifier "(DE-101)1328908526";
umbel:isLike , ;
dc:identifier "(OCoLC)1562736361";
dcterms:format ;
foaf:primaryTopic ;
dcterms:language ;
a bibo:Article;
dc:title "A Hydrogel Dressing Comprised of Silk Fibroin, Ag Nanoparticles, and Reduced Graphene Oxide for NIR Photothermal‐Enhanced Antibacterial Efficiency and Skin Regeneration";
dcterms:creator _:node1k0rmm5k0x125458364 .
_:node1k0rmm5k0x125458364 gndo:preferredName "Yan, Shaorong" .
marcRole:aut _:node1k0rmm5k0x125458365 .
_:node1k0rmm5k0x125458365 gndo:preferredName "Yan, Shaorong" .
marcRole:aut _:node1k0rmm5k0x125458366 .
_:node1k0rmm5k0x125458366 gndo:preferredName "Xu, Shuo" .
marcRole:aut _:node1k0rmm5k0x125458367 .
_:node1k0rmm5k0x125458367 gndo:preferredName "Wang, Yu" .
marcRole:aut _:node1k0rmm5k0x125458368 .
_:node1k0rmm5k0x125458368 gndo:preferredName "You, Jun" .
marcRole:aut _:node1k0rmm5k0x125458369 .
_:node1k0rmm5k0x125458369 gndo:preferredName "Guo, Chuanlong" .
marcRole:aut _:node1k0rmm5k0x125458370 .
_:node1k0rmm5k0x125458370 gndo:preferredName "Wu, Xiaochen";
owl:sameAs .
dcterms:extent "19 S.";
dcterms:isPartOf ;
dcterms:description "Abstract: Bacterial infection, inflammation, and excessive oxidative stress are the primary factors that contribute to delayed healing of skin wounds. In this study, a multifunctional wound dressing (SF/AgrGO hydrogel) is developed to promote the healing of infected skin wounds by combining the inherent antibacterial activity of Ag nanoparticles (NPs) with near‐infrared (NIR)‐assisted antibacterial therapy. Initially, L‐ascorbic acid is used as a reducing agent and PVP‐K17 as a stabilizer and dispersant, this facilitates the synthesis of reduced graphene oxide loaded with Ag NPs (AgrGO). AgrGO is then blended with a silk fibroin (SF) solution to form an instantly gelling SF/AgrGO hydrogel that exhibits rapid self‐healing, injectability, shape adaptability, NIR responsiveness, antioxidant, high tissue adhesion, and robust mechanical properties. In vitro and in vivo experiments show that the SF/AgrGO hydrogel demonstrates strong antioxidant and photothermal antibacterial capabilities, promoting wound healing through angiogenesis, stimulating collagen generation, alleviating inflammation, antioxidant, and promoting cell proliferation, indicating that the SF/AgrGO hydrogel dressing is an ideal candidate for clinical treatment of full‐thickness bacterial‐stained wounds."@de;
dcterms:license ;
wdrs:describedby .
dcterms:license ;
dcterms:modified "2026-03-01T00:50:52.000"^^xsd:dateTime .
dcterms:issued "2024";
bibo:issue "2024-05-09";
owl:sameAs .